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Hepcidin-1 (mouse) trifluoroacetate salt
CAS No. 1676104-75-8
Hepcidin-1 (mouse) trifluoroacetate salt( ——— )
Catalog No. M41734 CAS No. 1676104-75-8
Hepcidin-1 (mouse) is an endogenous peptide hormone involved in the regulation of iron homeostasis. Hepcidin-1 (mouse) upregulates mRNA levels of TRAP, cathepsin K, and MMP-9 and increases TRAP-5b protein secretion. Hepcidin-1 (mouse) downregulates the level of FPN1 protein and increases intracellular iron. Hepcidin-1 (mouse) facilitates osteoclast differentiation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameHepcidin-1 (mouse) trifluoroacetate salt
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NoteResearch use only, not for human use.
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Brief DescriptionHepcidin-1 (mouse) is an endogenous peptide hormone involved in the regulation of iron homeostasis. Hepcidin-1 (mouse) upregulates mRNA levels of TRAP, cathepsin K, and MMP-9 and increases TRAP-5b protein secretion. Hepcidin-1 (mouse) downregulates the level of FPN1 protein and increases intracellular iron. Hepcidin-1 (mouse) facilitates osteoclast differentiation.
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DescriptionHepcidin-1 (mouse) is an endogenous peptide hormone involved in the regulation of iron homeostasis. Hepcidin-1 (mouse) upregulates mRNA levels of TRAP, cathepsin K, and MMP-9 and increases TRAP-5b protein secretion.
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In VitroWestern Blot Analysis Cell Line:RAW264.7 cells Concentration:0, 200, 400, or 800 nM Incubation Time:20 h Result:Decreased Ferroportin 1 (FPN1) protein.Real Time qPCR Cell Line:RAW264.7 cells Concentration:0, 200, 400, or 800 nM Incubation Time:4 days Result:Increased the gene expression of TRAP, CTK, and MMP-9 in a dose-dependent manner.
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In Vivo———
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Synonyms———
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PathwayOthers
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TargetOther Targets
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RecptorMMP-9, cathepsin K
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Research Area———
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Indication———
Chemical Information
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CAS Number1676104-75-8
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Formula Weight2754.28
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Molecular FormulaC111H169N31O35S8
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Purity>98% (HPLC)
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Solubility———
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhao GY, et al. Effects of mouse hepcidin 1 treatment on osteoclast differentiation and intracellular iron concentration. Inflammation. 2015 Apr;38(2):718-27.?
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